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Indinavir is metabolized by CYP3A4Drugs that induce CYP3A4 activity would be expected to increase the clearance of indinavirresulting in lowered plasma concentrations of indinavirCoadministration of CRIXIVAN and other drugs that inhibit CYP3A4 may decrease the clearance of indinavir and may result in increased plasma concentrations of indinavir.

A statement to patients and health care providers is included on the product's bottle labelALERTFind out about medicines that should NOT be taken with CRIXIVANA Patient Package InsertPPIfor CRIXIVAN is available for patient information.

Skin and Skin Appendagerash including erythema multiforme and Stevens-Johnson syndromehyperpigmentationalopeciaingrown toenails and/or paronychiapruritus.

Indirect hyperbilirubinemia has occurred frequently during treatment with CRIXIVAN and has infrequently been associated with increases in serum transaminasessee also ADVERSE REACTIONSClinical Trials and Post-Marketing ExperienceIt is best canadian prices for pfizer viagra, best canadian prices for pfizer viagra, best canadian prices for pfizer viagra, best canadian prices for pfizer viagra, best canadian prices for pfizer viagra, best canadian prices for pfizer viagra. not known whether CRIXIVAN will exacerbate the physiologic hyperbilirubinemia seen in neonatesSee Pregnancy

Urogenital Systemnephrolithiasis/urolithiasisin some cases resulting in renal insufficiency or acute renal failurepyelonephritis with or without bacteremiasee WARNINGSinterstitial nephritis sometimes with indinavir crystal depositsin some patientsthe interstitial nephritis did not resolve following discontinuation of CRIXIVANrenal insufficiencyrenal failureleukocyturiasee PRECAUTIONScrystalluriadysuria.

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changes in body fat may also be seen while taking indinavir, especially increased fat in upper back and stomach areas while decreased fat in arms and legs.

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