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This is not a complete list of side effects and others may occurCall your doctor for medical advice about side effectsYou may report side effects to FDA at 1-800-FDA-1088.
Before taking acarbosetell your doctor if you have liver diseaseor any type of stomach or intestinal disorder.
Fertility studies conducted in rats after oral administration produced no untoward effect on fertility or on the overall capability to reproduce.
Sulfonylurea agents or insulin may cause hypoglycemiaPRECOSE given in combination with a sulfonylurea or insulin will cause a further lowering of blood glucose and may increase the potential for hypoglycemiaIf cytotec paing with mastercard. hypoglycemia occursappropriate adjustments in the dosage of these agents should be made.
Acarbose is metabolized exclusively within the gastrointestinal tractprincipally by intestinal bacteriabut also by digestive enzymesA fraction of these metabolitesapproximately 34of the dosewas absorbed and subsequently excreted in the urineAt least 13 metabolites have been separated chromatographically from urine specimensThe major metabolites have been identified as 4-methylpyrogallol derivativesthat issulfatemethyland glucuronide conjugatesOne metaboliteformed by cleavage of a glucose molecule from acarbosealso has alpha-glucosidase inhibitory activityThis metabolitetogether with the parent compoundrecovered from the urineaccounts for less than 2of the total administered dose.
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