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Methylprednisolone acetatea slightly soluble ester of methylprednisoloneis capable of producing a more prolonged local anti-inflammatory effect than equimolar doses of hydrocortisone acetateFollowing intrasynovial injectionrelief from pain may be experienced within 12 to vigra for men, vigra for men, vigra for men, vigra for men, vigra for men, vigra for men. 24 hoursThe duration of relief variesbut averages three to four weekswith a range of one to five or more weeksInjections of methylprednisolone acetate have been well toleratedIntrasynovialintra-articularinjections may occasionally result in an increased localized inflammatory response.

Frequency not reportedHepatomegalyelevation in liver enzymestoxic hepatitisRef]

Frequency not reportedAllergic or hypersensitivity reactionsanaphylactoid reactionanaphylaxisangioedemabronchospasmRef]

Areas not suitable for injection are those that are anatomically inaccessible such as spinal joints and those like the sacroiliac jointswhich are devoid of synovial spaceTreatment failures are most frequently the result of failure to enter the synovial spaceIf failures occur when injections into the synovial spaces are certainas determined by aspiration of fluidrepeated injections are usually futileLocal therapy does not alter the underlying disease processand whenever possible comprehensive therapy including physiotherapy and orthopedic correction should be employed.

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